Osteoarthritis (OA) is prevalent throughout the world. It is estimated that 300 million individuals worldwide are living with OA. It is the leading cause of disability in older adults and leads to pain, loss of function, and decreased quality of life. There is no specific cure for OA. The existing treatments can be broadly categorized into intra-articular therapy, reduction of modifiable risk factors, physical modalities, alternative therapies, and surgical treatments.